Exposome Dimensions

Key dimensions in the conceptualization of the exposome include places, exposures, actors, activities, social practices, and life stages, with a focus on how these elements interrelate. Social practices play a significant role, influencing and being influenced by other components. Places inherently encompass various aspects of the exposure domains used in Equal-Life, such as indoor and outdoor environmental quality, the natural environment, the built environment, the social environment, and lifestyle. Internal exposures (e.g., proteins and metabolites) are less directly tied to specific places but can still be influenced by social practices and life stages. The concept of the life course emphasizes the importance of considering child development when examining the interplay between social practices, exposures, places, actors, and activities.