What are relevant indicators for physical exposome?

1. The outdoor environmental quality: e.g. noise and sound quality, air quality, housing

practices.

2. The indoor environmental quality: e.g. mother smoking during pregnancy, child

passive smoking, crowding, indoor air quality, indoor sound quality, household

chemicals, prenatal chemicals.

3. The built environment: e.g. level of urbanization, type of neighbourhood, street

connectivity, junctions’ density, road types, land‐use, building quality (housing quality,

age of building), crowding, physical safety, walkability, access to facilities such as

playground, sportsground, parks, culture and relevant moderators such as length of

residency.

4. The natural environment: e.g. green space, blue space, access to green and blue space

(residential/school/on the move), playability, biodiversity, safety, activities in green

and blue spaces.

5. Lifestyle factors: e.g. sleep (duration/quality/rhythm), substance use, healthy food

intake, activity patterns, mobility/mode of commuting, leisure time, sports, sunlight

exposure, playtime online